MIT

MIT Chemists Finish A 50-Year Synthesis Of Verticillin A, A Fungal Molecule Aimed At Deadly Childhood Brain Tumors
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MIT Chemists Finish A 50-Year Synthesis Of Verticillin A, A Fungal Molecule Aimed At Deadly Childhood Brain Tumors

MIT and Harvard Medical School reported the first total synthesis of (+)-verticillin A, isolated in 1970. A 16-step route from beta-hydroxytryptophan produced the natural product and designed variants. Derivatives cut…
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