cancer

MIT Built Verticillin A After 50 Years, and the Natural Molecule Was Not the One That Hit Glioma Cells Hardest
Health News

MIT Built Verticillin A After 50 Years, and the Natural Molecule Was Not the One That Hit Glioma Cells Hardest

MIT and Dana-Farber reported the first total synthesis of verticillin A, isolated in 1970. N-sulfonylated variants, not the natural product, were the most potent against diffuse midline glioma cells in…
IDO1 Cancer Drugs Restarted Astrocyte Glucose In Alzheimer’s Models While Kisunla’s Cleared Plaques Held And England Still Haggles
Health News

IDO1 Cancer Drugs Restarted Astrocyte Glucose In Alzheimer’s Models While Kisunla’s Cleared Plaques Held And England Still Haggles

Kisunla, approved in July 2024, can be stopped once amyloid plaques clear, and extension data showed most reductions holding for up to three years. IDO1 cancer inhibitors restored astrocyte glucose…
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