Otte minutters tilbagekaldt vrede skåret blodkar dilatation i halve, columbia forskere finde - sorg og angst ikke

En otte minutters hukommelse er nok til at skade foring af dine arterier. Det er ikke en metafor. Det er resultatet af et randomiseret forsøg Columbia kardiologer offentliggjort i Journal of the American Heart Association den 1. maj 2024. At minde om en personlig fornærmelse skar blodkarrene i stand til at udvide med mere end halvdelen. Det gjorde angst ikke. Det gjorde det ikke at læse triste sætninger. Det gjorde 100 ikke. Vrede var den eneste negative følelse i rummet, der efterlod et vaskulær fingeraftryk.

Dr. Daichi Shimbo, a cardiologist and professor of medicine at Columbia University Irving Medical Center, ran the study on an NIH grant to answer a question older papers had only circled. Observational work has tied angry outbursts to heart attacks for decades. A 1994 study found anger could double risk in some people. Nobody had isolated the plumbing. “We’ve long suspected, based on observational studies, that anger can negatively affect the heart,” said Laurie Friedman Donze, the NHLBI program officer. “This study in healthy adults helps fill a real knowledge gap and shows how this might occur.”

280 personer, fire scripts, en beskadiget foring

Researchers recruited 280 adults from the neighborhoods around Columbia, ages 18 to 73, average about 26, none of them carrying diagnosed cardiovascular disease or the usual risk-factor pile. Each person sat for 30 minutes in a quiet, temperature-controlled room — no talking, no phone, no reading, no sleep. Then they were randomized into one of four eight-minute tasks: relive a memory that made them angry, relive one that made them anxious, read a stack of depressing sentences, or count to 100 and stay flat.

Før opgaven og med mellemrum derefter målte holdet blodtryk, hjertefrekvens og hvor godt karrene i underarmen og fingrene kunne udvide sig. De trak blod til at se på endothelial-celle skade og på bone-marrow- afledte celler, der reparerer foring.

The anger group lost more than half their dilation capacity. The drop showed up almost immediately, peaked around 40 minutes, and then faded. Anxiety and sadness produced no statistically significant change — a split that surprised the investigators. The endothelium is the inner skin of a blood vessel. When it cannot relax, blood flow suffers, and that failure is treated as an early step toward atherosclerosis, the hardening that sits under most heart attacks and strokes. “Anger is bad for your blood vessel function,” Shimbo said. “It impairs the function of your arteries, which is linked to future heart attack risk.”

En gang er en spike. 10.000 gange er en fil.

The lab effect was temporary. Shimbo’s warning was not. “We showed that if you get angry once, it impairs your ability to dilate. But what if you get angry 10,000 times over a lifetime? This chronic insult to your arteries eventually may lead to permanent damage. That’s what we think is going on.” An occasional flash of temper is not the finding. The finding is a repeating insult to the same lining.

The paper did not pin the exact chemical path. Shimbo listed the usual suspects: the autonomic nervous system, cortisol, and arterial inflammation. The cohort was young and healthy, the emotions were staged in a clinic, and only short-term changes were measured. Whether the same eight minutes does worse in a 65-year-old on blood-pressure pills is a different study. The American Heart Association has spent the years since folding emotional regulation into its mind-heart-body framework for a reason. Endothelial function is one of the places that framework stops being a slogan.

Den praktiske liste er ikke eksotisk. Mindfulness, motion, yoga, og kognitiv adfærdsterapi alle har beviser bag dem som måder at ændre, hvor ofte 8-minutters spike sker. Folk, der allerede lever med hjertesygdomme, har mere at miste fra at behandle raseri som en personlighedsforstyrrelse.

AEGIS Alliance har dækket andre filer, hvor den officielle medicin halter kemi, herunder USA 's regerings eget cannabispatent og a cannabisundersøgelse af opioidafhængighed mainstream pressen behandles som en ulempe. Mere af dette beat er i Nyheder om sundhed.

Denne artikel er generel information, ikke medicinsk rådgivning. Hvis du har spørgsmål om hjerte sundhed eller vrede, tale med en kliniker.